Recombinant Human Activin-A
Cat.No. : | Activin-A-3121H |
Product Overview : | Activin-A |
- Specification
- Gene Information
- Related Products
- Download
Species : | Human |
Source : | Insect Cells |
Tag : | Non |
Protein Length : | 426 |
Description : | The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome. |
Form : | Lyophilized |
Molecular Mass : | 47,442 Da |
Purity : | >95% by SDS-PAGE & HPLC analyses |
Notes : | Small volumes of Activin-A recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice. |
Warning : | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Gene Name | INHBA inhibin, beta A [ Homo sapiens ] |
Official Symbol | INHBA |
Synonyms | INHBA; EDF; FRP; inhibin beta A chain; Inhibin, beta-1; activin beta-A chain; FSH-releasing protein; erythroid differentiation factorerythroid differentiation protein; follicle-stimulating hormone-releasing protein; inhibin, beta A (activin A, activin AB alpha polypeptide) |
Gene ID | 3624 |
mRNA Refseq | NM_002192 |
Protein Refseq | NP_002183 |
MIM | 147290 |
UniProt ID | P08476 |
Chromosome Location | 7p15-p13 |
Pathway | ALK1 signaling events, organism-specific biosystem; Cardiac Progenitor Differentiation, organism-specific biosystem |
Function | cytokine activity; growth factor activity |
◆ Recombinant Proteins | ||
Inhba-7805R | Recombinant Rat Inhba protein, His-tagged | +Inquiry |
INHBA-7804P | Recombinant Pig INHBA protein, His-tagged | +Inquiry |
INHBA-7801C | Recombinant Cattle INHBA protein, His-tagged | +Inquiry |
INHBA-2721R | Recombinant Rat INHBA Protein, His (Fc)-Avi-tagged | +Inquiry |
INHBA-145H | Active Recombinant Human Inhibin Beta A chain, His tagged, Animal Free | +Inquiry |
◆ Cell & Tissue Lysates | ||
INHBA-2078MCL | Recombinant Mouse INHBA cell lysate | +Inquiry |
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Ask a Question for All INHBA Products
Required fields are marked with *
My Review for All INHBA Products
Required fields are marked with *
0
Inquiry Basket