Recombinant Human Actin-like 6A, T7-tagged

• Cat.No.: ACTL6A-61H
• Product Overview: Recombinant Human Actin-like 6A produced inE.Colicontains T7 tag at N-terminus and is purified by proprietary chromatographic techniques.

Specification

• Cat. No.: ACTL6A-61H
• Description: The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Recombinant Human ACTL6A produced in E.Coli is a non-glycosylated, polypeptide chain containing 430 (1-429) amino acids and having a total molecular mass of 49.3 kda.
• Source: E.Coli.
• Physical Appearance: Sterile Filtered clear solution.
• Formulation: Recombinant Human Actin Like 6A at a concentration of 0.1mg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol.
• Applications: • ELISA • Inhibition Assays • Western Blotting.
• Storage: rhACTL6A although stable at 14℃ for 1 week, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Gene Information

• Gene Name: ACTL6A actin-like 6A [ Homo sapiens ]
• Synonyms: actin-like 6A; BAF53; hArpN beta; BRG1-associated factor; INO80 complex subunit K; actin-related protein 4; BAF complex 53 kDa subunit; Arp4; ACTL6; BAF53A; INO80K; MGC5382; ARPN-BETA; ACTL6A;Actin-like protein 6A;53 kDa BRG1-associated factor A; Actin-related protein Baf53a; ArpNbeta; INO80 complex subunit K
• Gene ID: 86
• mRNA Refseq: NM_004301
• Protein Refseq: NP_004292
• MIM: 604958
• UniProt ID: O96019
• Chromosome Location: 3q26.33
• Function: ATP binding; chromatin binding; protein binding