Recombinant Human ACP2 Protein, His-tagged

Cat.No. : ACP2-46H
Product Overview : Recombinant Human ACP2 Protein (Tyr40-Ala250) with N-His tag was expressed in E. coli.
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Species : Human
Source : E.coli
Tag : His
Protein Length : Tyr40-Ala250
Description : The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene in mice showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism.
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 28.5 kDa
Accurate Molecular Mass: 29 kDa
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer : PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Gene Name ACP2 acid phosphatase 2, lysosomal [ Homo sapiens (human) ]
Official Symbol ACP2
Synonyms ACP2; acid phosphatase 2, lysosomal; lysosomal acid phosphatase; LAP
Gene ID 53
mRNA Refseq NM_001131064
Protein Refseq NP_001124536
MIM 171650
UniProt ID P11117

Not For Human Consumption!

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