ACP2
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Official Full Name
acid phosphatase 2, lysosomal -
Overview
This gene encodes the beta subunit of lysosomal acid phosphatase (LAP). LAP is chemically and genetically distinct from red cell acid phosphatase. The encoded protein belongs to a family of distinct isoenzymes which hydrolyze orthophosphoric monoesters to alcohol and phosphate. Mutations in this gene or in the related alpha subunit gene cause acid phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. -
Synonyms
ACP2;acid phosphatase 2, lysosomal;lysosomal acid phosphatase;LAP
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Mouse
- Mus musculus
- Xenopus laevis
- Rat
- Wheat Germ
- Mammalian Cell
- HEK293
- HEK293T
- E.coli
- In Vitro Cell Free System
- E.coli expression system
- GST
- His
- Non
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ACP2-179H | Recombinant Human ACP2 Protein, GST-Tagged | Wheat Germ | Human | GST |
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| ACP2-2124Z | Recombinant Zebrafish ACP2 | Mammalian Cell | Zebrafish | His |
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| ACP2-3192C | Recombinant Chicken ACP2 | Mammalian Cell | Chicken | His |
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| ACP2-9082HCL | Recombinant Human ACP2 293 Cell Lysate | HEK293 | Human | Non |
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| ACP2-216H | Recombinant Human acid phosphatase 2, lysosomal Protein, His tagged | HEK293 | Human | His | 31-380aa |
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| ACP2-2666H | Recombinant Human ACP2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| ACP2-46H | Recombinant Human ACP2 Protein, His-tagged | E.coli | Human | His | Tyr40-Ala250 |
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| Acp2-515M | Recombinant Mouse Acp2 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| ACP2-801HF | Recombinant Full Length Human ACP2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 423 amino acids |
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| RFL-2142MF | Recombinant Full Length Mouse Lysosomal Acid Phosphatase(Acp2) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length (31-423) |
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| RFL-26639HF | Recombinant Full Length Human Lysosomal Acid Phosphatase(Acp2) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (31-423) |
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| RFL-29323XF | Recombinant Full Length Xenopus Laevis Lysosomal Acid Phosphatase(Acp2) Protein, His-Tagged | E.coli expression system | Xenopus laevis | His | Full L. Full Length of Mature Protein (33-432) |
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| RFL-3666RF | Recombinant Full Length Rat Lysosomal Acid Phosphatase(Acp2) Protein, His-Tagged | E.coli expression system | Rat | His | Full L. Full Length (31-423) |
|
Involved Pathway
ACP2 involved in several pathways and played different roles in them. We selected most pathways ACP2 participated on our site, such as Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Lysosome | AP1G2,DNASE2A,FUCA1,CTPS1B,IDS,NPC1,GNPTAB,TCEAL4,ATP6V0A2,CTSC |
Protein Function
ACP2 has several biochemical functions, for example, acid phosphatase activity,phosphoprotein phosphatase activity,phosphotyrosine binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACP2 itself. We selected most functions ACP2 had, and list some proteins which have the same functions with ACP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphotyrosine binding | SAMSN1,CBL,PTPN3,LDLRAP1,MAPK1,ZAP70,CBLC,CBLB,GRB2,SHC1 |
| acid phosphatase activity | MINPP1,ACPL2,ACP1,PPIP5K2,ACP5A,ACP5,ACP6,PXYLP1,MINPP1A,ACP5B |
| phosphoprotein phosphatase activity | PTEN,PPP1CAA,PDXP,PTPRFB,PPP5C,PPM1LB,PTPN11B,PHLPP1,PTPRZ1,PTPRU |
Interacting Protein
ACP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACP2.
cona_canen;CBX1
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