Recombinant Human ACE2 Protein (Gln18-Ser740), C-Fc tagged, Animal-free, Carrier-free

• Cat.No.: ACE2-264H
• Product Overview: Recombinant Human ACE2 Protein (Gln18-Ser740) with C-Fc tag was expressed in HEK293 and Animal-free as well as Carrier-free.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: Gln18-Ser740
• Description: Angiotensin-Converting Enzyme 2 (ACE2) has a function as an enzyme that hydrolysis the angiotensin II into angiotensin which do the effect of anti-oxidation and anti-inflammatory in cardiovascular system through the inhibition of MAPK pathway and TGF β signaling pathway. ACE2 is highly expression in intestines, kidney, and heart. It is also fonud highy expression in patients with lung cancer.
• Form: Lyophilized
• Molecular Mass: The protein has a calculated MW of 109.67 kDa.
  The protein migrates as 120-170 kDa under reducing condition (SDS-PAGE analysis).
• Endotoxin: < 0.1 EU/μg of the protein by the LAL method.
• Purity: >98% as determined by SDS-PAGE analysis.
• Storage: This product is stable after storage at:
  -20 centigrade for 12 months in lyophilized state from date of receipt.
  -20 or -80 centigrade for 1 month under sterile conditions after reconstitution.
  Avoid repeated freeze/thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Reconstitution: It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
• Shipping: The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage.

Gene Information

• Gene Name: ACE2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 [ Homo sapiens (human) ]
• Official Symbol: ACE2
• Synonyms: ACE2; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin-converting enzyme 2; metalloprotease MPROT15; ACE-related carboxypeptidase; angiotensin I converting enzyme 2; angiotensin-converting enzyme homolog; ACEH
• Gene ID: 59272
• mRNA Refseq: NM_021804
• Protein Refseq: NP_068576
• MIM: 300335
• UniProt ID: Q9BYF1