Recombinant Human ABI Family, Member 3, His-tagged

• Cat.No.: ABI3-7165H
• Product Overview: Recombinant human ABI3 protein, fused to His-tag, was expressed in E. coli. MW: 41.4 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-366aa
• Description: ABI3, also as known as ABI gene family member 3, belongs to the ABI family. This protein is a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain. The Abi family members are thought to negatively regulate cell growth and transformation, including cellular transformation through v-Abl as well as mediate cell motility by regulating actin polymerization in lamellipodia and filopodia. ABI3 inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol.
• Molecular Mass: 41.4 kDa (389aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAELQQL QEFEIPTGRE ALRGNHSALL RVADYCEDNY VQATDKRKAL EETMAFTTQA LASVAYQVGN LAGHTLRMLD LQGAALRQVE ARVSTLGQMV NMHMEKVARR EIGTLATVQR LPPGQKVIAP ENLPPLTPYC RRPLNFGCLD DIGHGIKDLS TQLSRTGTLS RKSIKAPATP ASATLGRPPR IPEPVHLPVV PDGRLSAASS ASSLASAGSA EGVGGAPTPK GQAAPPAPPL PSSLDPPPPP AAVEVFQRPP TLEELSPPPP DEELPLPLDL PPPPPLDGDE LGLPPPPPGF GPDEPSWVPA SYLEKVVTLY PYTSQKDNEL SFSEGTVICV TRRYSDGWCE GVSSEGTGFF PGNYVEPSC
• Purity: >85% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: ABI3 ABI family, member 3 [ Homo sapiens ]
• Official Symbol: ABI3
• Synonyms: ABI3; ABI family, member 3; ABI gene family member 3; NESH; SSH3BP3; ABI gene family, member 3; new molecule including SH3
• Gene ID: 51225
• mRNA Refseq: NM_001135186
• Protein Refseq: NP_001128658
• MIM: 606363
• UniProt ID: Q9P2A4
• Chromosome Location: 17q21.3
• Function: protein binding