Recombinant Human ABCA12 protein, His & T7-tagged

• Cat.No.: ABCA12-7853H
• Product Overview: Recombinant Human ABCA12 aa. (Val1346~Thr1577 (Accession # Q86UK0)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily, which is the only major ABC subfamily found exclusively in multicellular eukaryotes. Alternative splicing of this gene results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Tag: His&T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 29.2kDa.
• Protein length: Val1346~Thr1577
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 9.4.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: ABCA12 ATP binding cassette subfamily A member 12 [ Homo sapiens (human) ]
• Official Symbol: ABCA12
• Synonyms: Plcd4; phospholipase C, delta 4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4; PLC-delta-4; phosphoinositide phospholipase C-delta-4
• Gene ID: 26154
• mRNA Refseq: NM_015657.3
• Protein Refseq: NP_056472.2
• UniProt ID: Q86UK0