Recombinant Human AATF Protein, His/GST-tagged

• Cat.No.: AATF-664H
• Product Overview: Recombinant Human AATF(Ser273~Ser477) fused with His/GST tag at N-terminal was expressed in E. coli.

Specification

• Description: The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 53.729kDa
• Identity: Reconstitute in PBS or others
• Protein length: Ser273~Ser477
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: AATF apoptosis antagonizing transcription factor [ Homo sapiens ]
• Official Symbol: AATF
• Synonyms: AATF; apoptosis antagonizing transcription factor; protein AATF; CHE 1; CHE1; DED; rb-binding protein Che-1; apoptosis-antagonizing transcription factor; CHE-1
• Gene ID: 26574
• mRNA Refseq: NM_012138
• Protein Refseq: NP_036270
• MIM: 608463
• UniProt ID: Q9NY61