Recombinant house mouse AATK, GST-tagged

• Cat.No.: AATK-3037H
• Product Overview: AATK

Specification

• Species: Mouse
• Source: Sf9 Cells
• Tag: GST
• Protein Length: 5706
• Description: Recombinant mouse AATK (8-411) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: AATK or apoptosis-associated tyrosine kinase contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. AATK is induced during apoptosis, and expression of this protein is a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells (1). AATK is highly detected in brain, lung, kidney, and pancreas (2). AATK is also shown to produce neuronal differentiation in a neuroblastoma cell line.
• Form: 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: ~71 kDa
• Applications: Western Blot (WB)
• Notes: Small volumes of AATK recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: Aatk apoptosis-associated tyrosine kinase [ Mus musculus ]
• Official Symbol: Aatk
• Synonyms: AATYK; LMTK1; KIAA0641; Aatk; Aatk; AATY; serine/threonine-protein kinase LMTK1; lemur tyrosine kinase 1; apoptosis-associated tyrosine kinase 1B; brain apoptosis-associated tyrosine kinase
• Gene ID: 11302
• mRNA Refseq: NM_001198785
• Protein Refseq: NP_001185714
• UniProt ID: Q80YE4
• Chromosome Location: 11 E2; 11
• Function: ATP binding; kinase activity; nucleotide binding