Recombinant H. pylori CagA Protein

• Cat.No.: CagA-25H
• Product Overview: This recombinant protein contains immunodominant regions of H. pylori CagA protein with a MW of 38 kDa. It is recognized by positive samples in ELISA tests.

Specification

• Species: H.pylori
• Source: E.coli
• Description: It is known that H. pylori strains exhibit a significant degree of diversity. The great variability in the H. pylori genome may explain why not all infected individuals suffer from ulcer. Some H. pylori strains contain particular pathogenic genes such as cytokine associated gene A (CagA), while others lack these genes. The CagA protein of H. pylori has been found to be associated with more severe clinical manifestations, such as ulcer disease and gastric cancer. Thus, discrimination between potentially virulent strains may be relevant.
• Form: Affinity purified, liquid
• Molecular Mass: 38 kDa
• Purity: >90% pure by SDS-PAGE
• Applications: Suitable for use in ELISA, Lateral Flow, WB, and other immune tests.
• Storage: Upon receipt, quick spin before open vial, aliquot and store at ≤ -20 centigrade. Avoid multiple freeze/thaw cycles
• Storage Buffer: PBS, pH 7.3
• Preservative: 0.1% ProClin 300

Gene Information

• Synonyms: 120 kDa; CAG pathogenicity island protein 26; cag26; cagA; cai; Cytotoxicity-associated immunodominant antigen; H. pylori CagA; H. pylori cytokine associated gene A; Helicobacter pylori cytokine associated gene A