Recombinant Guinea pig Tnf Protein, His-tagged

• Cat.No.: Tnf-433G
• Product Overview: Recombinant Guinea pig Tnf Protein (Gly57-Leu234) with N-His tag was expressed in E. coli.

Specification

• Species: Guinea pig
• Source: E.coli
• Tag: His
• Protein Length: Gly57-Leu234
• Description: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 19.7 kDa
  Accurate Molecular Mass: 24 kDa
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Tnf tumor necrosis factor [ Cavia porcellus (domestic guinea pig) ]
• Official Symbol: Tnf
• Synonyms: TNF; tumor necrosis factor; TNF-a; TNF-alpha; cachectin; tumor necrosis factor alpha; tumor necrosis factor ligand superfamily member 2; TNFA; TNFSF2
• Gene ID: 100135630
• mRNA Refseq: NM_001173025
• Protein Refseq: NP_001166496
• UniProt ID: P51435