Recombinant Full Length Mouse HDAC8 Protein, His-tagged

• Cat.No.: HDAC8-20MFL
• Product Overview: Recombinant Full Length Mouse Hdac8 Protein, fused to His-tag, was expressed in Baculovirus.

Specification

• Description: Predicted to enable chromatin binding activity; heat shock protein binding activity; and histone deacetylase activity. Predicted to be involved in several processes, including histone deacetylation; negative regulation of macromolecule metabolic process; and regulation of chromosome organization. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of histone deacetylase complex. Is expressed in several structures, including 2-cell stage embryo; brain; embryo ectoderm; foregut; and retina. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 5 and Wilson-Turner syndrome. Orthologous to human HDAC8 (histone deacetylase 8).
• Source: Insect cells
• Species: Mouse
• Tag: His
• Protein length: 1-377 aa
• Form: Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol.
• Molecular Mass: 42.5 kDa
• Endotoxin: < 1 EU per 1ug of protein (determined by LAL method).
• Purity: > 90% by SDS-PAGE
• Applications: SDS-PAGE
• Notes: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
• Storage: Can be stored at 2 centigrade to 8 centigrade for 1 week. For long term storage, aliquot and store at -20 centigrade to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25mg/ml (determined by absorbance at 280nm).

Gene Information

• Gene Name: Hdac8 histone deacetylase 8 [ Mus musculus (house mouse) ]
• Official Symbol: Hdac8
• Synonyms: Histone deacetylase 8 isoform 1, Hdac8, 2610007D20Rik, HD8, Protein deacetylase HDAC8, Protein decrotonylase HDAC8
• Gene ID: 70315
• mRNA Refseq: NM_027382.4
• Protein Refseq: NP_081658.1
• UniProt ID: Q8VH37