Recombinant Full Length Human XRN1 Protein, GST-tagged

• Cat.No.: XRN1-552HF
• Product Overview: Human XRN1 full-length ORF ( AAH48104.1, 1 a.a. - 459 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: SEP1 localizes to cytoplasmic foci containing a complex of mRNA-degrading enzymes. In addition to mRNA metabolism, yeast Sep1 has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 80.2 kDa
• Protein length: 459 amino acids
• AA Sequence: MGVPKFYRWI SERYPCLSEV VKEHQIPEFD NLYLDMNGII HQCSHPNDDD VHFRISDDKI FTDIFHYLEV LFRIIKPRKV FFMAVDGVAP RAKMNQQRGR RFRSAKEAED KIKKAIEKGE TLPTEARFDS NCITPGTEFM AKLHEHLKYF VNMKISTDKS WQGVTIYFSG HETPGEGEHK IMEFIRSEKA KPDHDPNTRH CLYGLDADLI MLGLTSHEAH FSLLREEVRF GGKKTQRVCA PEETTFHLLH LSLMREYIDY EFSVLKEKIT FKYDIERIID DWILMGFLVG NDFIPHLPHL HINHDALPLL YGTYVTILPE LGGYINESGH LNLPRFEKYL VKLSDFDREH FSEVFVDLKW FESKVGNKYL NEAAGVAAEE ARNYKEKKKL KGQENSLCWT ALDKNEGEMI TSKDNLEDET EDDDLFETEF RQYKRTYYMT KMGVDVVSEY VFANAFILK
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: XRN1 5'-3' exoribonuclease 1 [ Homo sapiens (human) ]
• Official Symbol: XRN1
• Synonyms: XRN1; SEP1; 5'-3' exoribonuclease 1; strand-exchange protein 1 homolog
• Gene ID: 54464
• mRNA Refseq: NM_019001
• Protein Refseq: NP_061874
• MIM: 607994
• UniProt ID: Q8IZH2