Recombinant Full Length Human XCR1 Protein

• Cat.No.: XCR1-13HFL
• Product Overview: Recombinant Full Length Human XCR1 Protein was expressed in Wheat Germ (in vitro).

Specification

• Species: Human
• Source: Wheat Germ
• Description: The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains. The encoded protein transduces a signal by increasing the intracellular calcium ion level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Some studies have implicated a cluster of genes at 3p21.31, including this gene, as associated with COVID-19 risk. The encoded protein may also play a role in cell proliferation and migration in several types of cancer.
• Form: Liquid
• Molecular Mass: 38.5 kDa
• AA Sequence: MESSGNPESTTFFYYDLQSQPCENQAWVFATLATTVLYCLVFLLSLVGNSLVLWVLVKYESLESLTNIFILNLCLSDLVFACLLPVWISPYHWGWVLGDFLCKLLNMIFSISLYSSIFFLTIMTIHRYLSVVSPLSTLRVPTLRCRVLVTMAVWVASILSSILDTIFHKVLSSGCDYSELTWYLTSVYQHNLFFLLSLGIILFCYVEILRTLFRSRSKRRHRTVKLIFAIVVAYFLSWGPYNFTLFLQTLFRTQIIRSCEAKQQLEYALLICRNLAFSHCCFNPVLYVFVGVKFRTHLKHVLRQFWFCRLQAPSPASIPHSPGAFAYEGASFY
• Applications: Antibody Production
• Usage: Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 25 mM Tris-HCl of pH8.0 containing 2% glycerol.
• Preparation: in vitro wheat germ expression system with proprietary liposome technology
• Protein Pathways: Chemokine signaling pathway
  Cytokine-cytokine receptor interaction
• Full Length: Full L.

Gene Information

• Gene Name: XCR1 X-C motif chemokine receptor 1 [ Homo sapiens (human) ]
• Official Symbol: XCR1
• Synonyms: GPR5; CCXCR1
• Gene ID: 2829
• mRNA Refseq: NM_005283.3
• Protein Refseq: NP_005274.1
• MIM: 600552
• UniProt ID: P46094