Recombinant Full Length Human WNT6 Protein, His&GST-tagged

• Cat.No.: WNT6-6HFL
• Product Overview: Recombinant Full Length Human WNT6 Protein, His&GST-tagged,expressed in E. coli.

Specification

• Description: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Molecular Mass: 67.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80°C after receiving vials.
• Concentration: >0.05 μg/μL as determined by microplate BCA method
• Storage Buffer: 50 mM Tris-HCl, pH 8.0, 8 M urea
• GeneID: 7475

Gene Information

• Gene Name: WNT6 Wnt family member 6 [ Homo sapiens (human) ]
• Official Symbol: WNT6
• Synonyms: WNT6,wingless-type MMTV integration site family member 6, protein Wnt-6
• mRNA Refseq: NM_006522
• Protein Refseq: NP_006513
• MIM: 604663
• UniProt ID: Q9Y6F9