Recombinant Full Length Human TUBB1 Protein, GST-tagged

• Cat.No.: TUBB1-6776HF
• Product Overview: Human TUBB1 full-length ORF ( NP_110400.1, 1 a.a. - 451 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. Alternative splicing of this gene results in multiple transcript variants.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 76.7 kDa
• Protein length: 451 amino acids
• AA Sequence: MREIVHIQIGQCGNQIGAKFWEMIG EEHGIDLAGSDRGASALQLERISVY YNEAYGRKYVPRAVLVDLEPGTMDS IRSSKLGALFQPDSFVHGNSGAGNN WAKGHYTEGAELIENVLEVVRHESE SCDCLQGFQIVHSLGGGTGSGMGTL LMNKIREEYPDRIMNSFSVMPSPKV SDTVVEPYNAVLSIHQLIENADACF CIDNEALYDICFRTLKLTTPTYGDL NHLVSLTMSGITTSLRFPGQLNADL RKLAVNMVPFPRLHFFMPGFAPLTA QGSQQYRALSVAELTQQMFDARNTM AACDLRRGRYLTVACIFRGKMSTKE VDQQLLSVQTRNSSCFVEWIPNNVK VAVCDIPPRGLSMAATFIGNNTAIQ EIFNRVSEHFSAMFKRKAFVHWYTS EGMDINEFGEAENNIHDLVSEYQQF QDAKAVLEEDEEVTEEAEMEPEDKG H
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: TUBB1 tubulin, beta 1 class VI [ Homo sapiens ]
• Official Symbol: TUBB1
• Synonyms: TUBB1; tubulin, beta 1 class VI; tubulin, beta 1; tubulin beta-1 chain; class VI beta tubulin; dJ543J19.4; class VI beta-tubulin; beta tubulin 1, class VI
• Gene ID: 81027
• mRNA Refseq: NM_030773
• Protein Refseq: NP_110400
• MIM: 612901
• UniProt ID: Q9H4B7