TUBB1
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Official Full Name
tubulin, beta 1 class VI -
Overview
This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y. -
Synonyms
TUBB1;tubulin, beta 1 class VI;tubulin, beta 1;tubulin beta-1 chain;class VI beta tubulin;dJ543J19.4;M(beta)1;2810484G07Rik;Beta tubulin 1, class VI;class VI beta-tubulin
Recombinant Proteins
- Human
- Mouse
- Chicken
- E.coli
- Mammalian Cells
- HEK293
- Wheat germ
- In Vitro Cell Free System
- His&T7
- His
- Non
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TUBB1-1303H | Recombinant Human TUBB1 protein, His & T7-tagged | E.coli | Human | His&T7 | Ser166~His451 |
|
| Tubb1-1304M | Recombinant Mouse Tubb1 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Pro182~Glu437 |
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| TUBB1-6995C | Recombinant Chicken TUBB1 | Mammalian Cells | Chicken | His |
|
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| TUBB1-652HCL | Recombinant Human TUBB1 293 Cell Lysate | HEK293 | Human | Non |
|
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| TUBB1-03H | Recombinant Human TUBB1 Protein, GST-tagged | Wheat germ | Human | GST |
|
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| TUBB1-6609H | Recombinant Human TUBB1 Protein (Ser166-His452), His tagged | E.coli | Human | His | Ser166-His452 |
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| TUBB1-6610H | Recombinant Human TUBB1 Protein (Ser166-His451), N-His tagged | E.coli | Human | His | Ser166-His451 |
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| TUBB1-6776HF | Recombinant Full Length Human TUBB1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 451 amino acids |
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Involved Pathway
TUBB1 involved in several pathways and played different roles in them. We selected most pathways TUBB1 participated on our site, such as Phagosome,Gap junction,Pathogenic Escherichia coli infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TUBB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Phagosome | cgr2b,THBS3,ATP6V1C1A,ATP6V1B2,ACTG1,SFTPA1,BLB2,SEC22B,ACTB,ATP6V0E |
| Gap junction | PLCB1,SRC,TUBB,MAPK1,GNA11B,NRAS,GRB2A,DRD2A,MAP2K1,HTR2B |
| Pathogenic Escherichia coli infection | TUBA3D,WASL,NCL,ITGB1,HCLS1,TUBAL3,ACTB,TUBB2A,TUBA1A,CLDN1 |
Protein Function
TUBB1 has several biochemical functions, for example, GTP binding,GTPase activity,structural constituent of cytoskeleton. Some of the functions are cooperated with other proteins, some of the functions could acted by TUBB1 itself. We selected most functions TUBB1 had, and list some proteins which have the same functions with TUBB1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP binding | IFT22,RHOBTB1,SRL,RHOT1,RALBB,RAB7L1,EEF1A2,GNAI2A,DNM1A,RAB28 |
| structural constituent of cytoskeleton | DES,TUBB5,NGS,SPTBN2,TLN2A,TNNT2A,ACTR2,TUBA8L3,ADD3,TUBGCP2 |
| GTPase activity | HBS1L,TUBB,RND3,MRAS,SEPT4,RAB32,RAB28,RHOD,DNM1B,GIMAP7 |
Interacting Protein
TUBB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TUBB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TUBB1.
SNW1;a8k1f4_human;DYNC1I1;MLF1;YWHAZ;PSMD2;CDC37;Hacd3;q96be0_human;AARSD1;LRRK2;15-deoxy-delta(12,14;ere_dna;Psmd14;GABARAP;HTR7;GABARAPL2;MDM2;STK4
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