Recombinant Full Length Human tripartite motif containing 63, E3 ubiquitin protein ligase Protein, SUMO-tagged

• Cat.No.: TRIM63-01H
• Product Overview: Recombinant Full Length Human TRIM63 Protein with N-SUMO-tag was expressed E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: SUMO
• Protein Length: Full Length
• Description: This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase.
• Tag: N-SUMO
• Molecular Mass: 51 kDa
• AA Sequence: MSDSEVNQEAKPEVKPEVKPETHINLKVSDGSSEIFFKIKKTTPLRRLMEAFAKRQGKEMDSLRFLYDGIRIQADQTPEDLDMEDNDIIEAHREQIGGMDYKSSLIQDGNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAANPYWTSRGSSVSMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQKGSHPMCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISMLVAGNDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQEKKLSFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLGKTEQGFENMDFFTLDLEHIADALRAIDFGTDEEEEEFIEEEDQEEEESTEGKEEGHQ
• Purity: > 90 % by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 1.96 mg/mL by BCA
• Storage Buffer: Sterile 50mM Tris, 300mM NaCl, pH8.0

Gene Information

• Gene Name: TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase [Homo sapiens (human)]
• Official Symbol: TRIM63
• Synonyms: TRIM63; tripartite motif containing 63, E3 ubiquitin protein ligase; ring finger protein 28 , RNF28, tripartite motif containing 63 , tripartite motif containing 63; E3 ubiquitin-protein ligase TRIM63; IRF; iris ring finger protein; MURF 1; muscle specific RING finger protein 1; SMRZ; striated muscle RING zinc finger protein; ring finger protein 28; tripartite motif-containing 63; muscle specific ring finger protein 2; muscle-specific RING finger protein 1; tripartite motif-containing protein 63; MURF1; MURF2; RNF28; FLJ32380
• Gene ID: 84676
• mRNA Refseq: NM_032588
• Protein Refseq: NP_115977
• MIM: 606131
• UniProt ID: Q969Q1