Recombinant Full Length Human TCEA3 Protein

• Cat.No.: TCEA3-520HF
• Product Overview: Recombinant full length Human TFIISH with a N terminal proprietary tag; Predicted MWt 64.39 kDa.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Protein Length: 348 amino acids
• Description: The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Form: Liquid
• Molecular Mass: 64.390kDa inclusive of tags
• AA Sequence: MGQEEELLRIAKKLEKMVARKNTEGALDLLKKLHSCQMSI QLLQTTRIGVAVNGVRKHCSDKEVVSLAKVLIKNWKRLLD SPGPPKGEKGEEREKAKKKEKGLECSDWKPEAGLSPPRKK REDPKTRRDSVDSKSSASSSPKRPSVERSNSSKSKAESPK TPSSPLTPTFASSMCLLAPCYLTGDSVRDKCVEMLSAALK ADDDYKDYGVNCDKMASEIEDHIYQELKSTDMKYRNRVRS RISNLKDPRNPGLRRNVLSGAISAGLIAKMTAEEMASDEL RELRNAMTQEAIREHQMAKTGGTTTDLFQCSKCKKKNCTY NQVQTRSADEPMTTFVLCNECGNRWKFC
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: TCEA3 transcription elongation factor A (SII), 3 [ Homo sapiens ]
• Official Symbol: TCEA3
• Synonyms: TCEA3; transcription elongation factor A (SII), 3; transcription elongation factor A protein 3; TFIIS.H
• Gene ID: 6920
• mRNA Refseq: NM_003196
• Protein Refseq: NP_003187
• MIM: 604128
• UniProt ID: O75764