Recombinant Full Length Human SP100 Protein

• Cat.No.: SP100-488HF
• Product Overview: Recombinant full length Human SP100, isoform A with N terminal proprietary tag, 78.87 kDa.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Protein Length: 480 amino acids
• Description: This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein.
• Form: Liquid
• Molecular Mass: 78.870kDa inclusive of tags
• AA Sequence: MAGGGGDLSTRRLNECISPVANEMNHLPAHSHDLQRMFTE DQGVDDRLLYDIVFKHFKRNKVEISNAIKKTFPFLEGLRD RDLITNKMFEDSQDSCRNLVPVQRVVYNVLSELEKTFNLP VLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEEE EREERSGLQLSLEQGTGENSFRSLTWPPSGSPSHAGTTPP ENGLSEHPCETEQINAKRKDTTSDKDDSLGSQQTNEQCAQ KAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPEAELH NHGIQINSCSVRLVDIKKEKPFSNSKVECQAQARTHHNQA SDIIVISSEDSEGSTDVDEPLEVFISAPRSEPVINNDNPL ESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVI GQDHDFSESSEEEAPAEASSGALRSKHGEKAPMTSRSTST WRIPSRKRRFSSSDFSDLSNGEELQETCSSSLRRGSGKED
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: SP100 SP100 nuclear antigen [ Homo sapiens ]
• Official Symbol: SP100
• Synonyms: SP100; SP100 nuclear antigen; nuclear antigen Sp100; nuclear autoantigen Sp-100
• Gene ID: 6672
• mRNA Refseq: NM_001080391
• Protein Refseq: NP_001073860
• MIM: 604585
• UniProt ID: P23497