Recombinant Full Length Human SLC18A1 Protein

• Cat.No.: SLC18A1-487HF
• Product Overview: Recombinant full length Human VMAT1 with N terminal proprietary tag; Predicted MWt 80.34 kDa.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Protein Length: 494 amino acids
• Description: The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al.
• Form: Liquid
• Molecular Mass: 80.340kDa inclusive of tags
• AA Sequence: MLRPILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTV VVPIVPTFLYDMEFKEVNSSLHLGHAGSSPHALASPAFST IFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA HKNNCLQGTGFLEEETTRVGVLFASKAVMQLLVNPFVGPL TNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQ GIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQP SKVSPESAKGTPLFMLLKDPYILVAAGLAFLPASVSYLIG TNLFGVLANKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGL IGPNAGLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVYAI ADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYA PLCYYLRSPPAKEEKLAILSQDCPMETRMYATQKPTKEFP LGEDSDEEPDHEE
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: SLC18A1 solute carrier family 18 (vesicular monoamine), member 1 [ Homo sapiens ]
• Official Symbol: SLC18A1
• Synonyms: SLC18A1; solute carrier family 18 (vesicular monoamine), member 1; VAT1, VMAT1; chromaffin granule amine transporter; CGAT
• Gene ID: 6570
• mRNA Refseq: NM_001135691
• Protein Refseq: NP_001129163
• MIM: 193002
• UniProt ID: P54219