Recombinant Full Length Human Regulator Of G-protein Signaling 4 / RGS4 Protein, His-tagged

• Cat.No.: RGS4-1563H
• Product Overview: Recombinant Human RGS4 was expressed inE.Coliusing an N-terminal His tag. MW= 23.6kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G α subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi α, Go α and Gq α subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.
• Sequence: 1-205.
• Purity: ~95%.
• Specific Activity: n/aH.
• Applications: E, WB, MS.
• Buffer: 10 mM Tris, pH 8.0, 0.002% NaN3, 3mM NaCl, 2.5mM.
• Storage: Store at -70˚C. As with any protein, exposing RGS4 recombinant protein to repeated freeze/thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• SDS-PAGE: SDS PAGE Analysis of RGS4 Recombinant Protein. 4-20% SDS gradient gel. Coomassie blue staining.

Gene Information

• Gene Name: RGS4 regulator of G-protein signaling 4 [ Homo sapiens ]
• Synonyms: RGS4; regulator of G-protein signaling 4; RGP4; SCZD9; MGC2124; MGC60244; DKFZp761F1924; schizophrenia disorder 9; regulator of G-protein signalling 4
• Gene ID: 5999
• mRNA Refseq: NM_001102445
• Protein Refseq: NP_001095915
• MIM: 602516
• UniProt ID: P49798
• Chromosome Location: 1q23.3
• Function: GTPase activator activity; calmodulin binding; signal transducer activity