Recombinant Full Length Human PLAU Protein, C-Flag-tagged
Cat.No. : | PLAU-1393HFL |
Product Overview : | Recombinant Full Length Human PLAU Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
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Species : | Human |
Source : | Mammalian Cells |
Tag : | Flag |
Description : | This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 46.3 kDa |
AA Sequence : | MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQHCEIDKSKTC YEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRRRPWCYVQVGLK PLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCG GSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLK IRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHY YGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIR SHTKEENGLALTRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, ES Cell Differentiation/IPS, Protease |
Protein Pathways : | Complement and coagulation cascades |
Full Length : | Full L. |
Gene Name | PLAU plasminogen activator, urokinase [ Homo sapiens (human) ] |
Official Symbol | PLAU |
Synonyms | ATF; QPD; UPA; URK; u-PA; BDPLT5 |
Gene ID | 5328 |
mRNA Refseq | NM_002658.6 |
Protein Refseq | NP_002649.2 |
MIM | 191840 |
UniProt ID | P00749 |
◆ Recombinant Proteins | ||
Plau-580M | Recombinant Mouse Plau protein, His & T7-tagged | +Inquiry |
PLAU-702H | Recombinant Human Plasminogen Activator, Urokinase | +Inquiry |
PLAU-6811M | Recombinant Mouse PLAU Protein, His (Fc)-Avi-tagged | +Inquiry |
PLAU-389H | Recombinant Human PLAU | +Inquiry |
PLAU-314H | Recombinant Human PLAU protein, His-tagged | +Inquiry |
◆ Native Proteins | ||
PLAU -15H | Native Human HMW urokinase, HRP conjugate | +Inquiry |
PLAU -14H | Native Human HMW urokinase, fluorescein labeled | +Inquiry |
PLAU-31689TH | Active Native Human Urokinase protein | +Inquiry |
PLAU-31687TH | Native Human PLAU | +Inquiry |
PLAU-31777TH | Native Human Human SERPINE1 | +Inquiry |
◆ Cell & Tissue Lysates | ||
PLAU-1734HCL | Recombinant Human PLAU cell lysate | +Inquiry |
Not For Human Consumption!
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