Recombinant Full Length Human PANK1 Protein, GST-tagged

• Cat.No.: PANK1-1541HF
• Product Overview: Recombinant full-length Human PANK1(1 a.a. - 373 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Tag: GST
• Protein Length: 373 amino acids
• Description: This gene encodes a member of the pantothenate kinase family. Pantothenate kinases are key regulatory enzymes in the biosynthesis of coenzyme A (CoA). The encoded protein catalyzes the first and rate-limiting enzymatic reaction in CoA biosynthesis and is regulated by CoA through feedback inhibition. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene and an intronic miRNA on the same strand are co-regulated by the tumor suppressor p53 (see PMID 20833636).
• Molecular Mass: 68.1 kDa
• AA Sequence: MKLINGKKQT FPWFGMDIGG TLVKLVYFEP KDITAEEEQE EVENLKSIRK YLTSNTAYGK TGIRDVHLEL KNLTMCGRKG NLHFIRFPSC AMHRFIQMGS EKNFSSLHTT LCATGGGAFK FEEDFRMIAD LQLHKLDELD CLIQGLLYVD SVGFNGKPEC YYFENPTNPE LCQKKPYCLD NPYPMLLVNM GSGVSILAVY SKDNYKRVTG TSLGGGTFLG LCCLLTGCET FEEALEMAAK GDSTNVDKLV KDIYGGDYER FGLQGSAVAS SFGNMMSKEK RDSISKEDLA RATLVTITNN IGSIARMCAL NENIDRVVFV GNFLRINMVS MKLLAYAMDF WSKGQLKALF LEHEGYFGAV GALLELFKMT DDK
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: PANK1 pantothenate kinase 1 [ Homo sapiens ]
• Official Symbol: PANK1
• Synonyms: PANK1; pantothenate kinase 1; PANK, pantothenate kinase; MGC24596; PANK1a; PANK1b; pantothenic acid kinase 1; PANK
• Gene ID: 53354
• mRNA Refseq: NM_148977
• Protein Refseq: NP_683878
• MIM: 606160
• UniProt ID: Q8TE04