Recombinant Full Length Human IMPDH2 Protein, GST-tagged
Cat.No. : | IMPDH2-5866HF |
Product Overview : | Human IMPDH2 full-length ORF ( AAH12840, 1 a.a. - 514 a.a.) recombinant protein with GST-tag at N-terminal. |
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Species : | Human |
Source : | In Vitro Cell Free System |
Tag : | GST |
Protein Length : | 514 amino acids |
Description : | This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5-monophosphate into xanthine-5-monophosphate, which is then converted into guanosine-5-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq |
Molecular Mass : | 82.17 kDa |
AA Sequence : | MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name | IMPDH2 IMP (inosine 5-monophosphate) dehydrogenase 2 [ Homo sapiens ] |
Official Symbol | IMPDH2 |
Synonyms | IMPDH2; IMP (inosine 5-monophosphate) dehydrogenase 2; inosine-5-monophosphate dehydrogenase 2; IMPD 2; IMPDH 2; IMP oxireductase 2; inosine 5 phosphate dehydrogenase 2; IMP (inosine monophosphate) dehydrogenase 2; inosine monophosphate dehydrogenase type II; IMPD2; IMPDH-II; |
Gene ID | 3615 |
mRNA Refseq | NM_000884 |
Protein Refseq | NP_000875 |
MIM | 146691 |
UniProt ID | P12268 |
◆ Recombinant Proteins | ||
Impdh2-3532M | Recombinant Mouse Impdh2 Protein, Myc/DDK-tagged | +Inquiry |
IMPDH2-11510Z | Recombinant Zebrafish IMPDH2 | +Inquiry |
IMPDH2-1274H | Recombinant Human IMP (Inosine 5'-Monophosphate) Dehydrogenase 2, His-tagged | +Inquiry |
IMPDH2-2482H | Recombinant Human IMPDH2 protein, His-tagged | +Inquiry |
IMPDH2-4161H | Recombinant Human IMPDH2 Protein, Myc/DDK-tagged, C13 and N15-labeled | +Inquiry |
◆ Cell & Tissue Lysates | ||
IMPDH2-5210HCL | Recombinant Human IMPDH2 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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