Recombinant Full Length Human FDFT1 Protein

• Cat.No.: FDFT1-167HF
• Product Overview: Recombinant full length Human FDFT1 with an N-terminal proprietary tag; 71.98 kDa.

Specification

• Description: This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.
• Source: In Vitro Cell Free System
• Species: Human
• Form: Liquid
• Molecular Mass: 71.980kDa inclusive of tags
• Protein length: 417 amino acids
• AA Sequence: MEFVKCLGHPEEFYNLVRFRVGGKRKVMPKMDQDSLSSSL KTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALD TLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQ VLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDK HVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGED TERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYV KKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRL RNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQ AVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTR QIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQY LTTLSQVTEDYVQTGEH
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: FDFT1 farnesyl-diphosphate farnesyltransferase 1 [ Homo sapiens ]
• Official Symbol: FDFT1
• Synonyms: FDFT1; farnesyl-diphosphate farnesyltransferase 1; squalene synthase
• Gene ID: 2222
• mRNA Refseq: NM_004462
• Protein Refseq: NP_004453
• MIM: 184420
• UniProt ID: P37268