Recombinant Human FDFT1 Protein (His269-His417), His tagged
Cat.No. : | FDFT1-3282H |
Product Overview : | Recombinant human FDFT1 (His269-His417) protein fused with His tag was expressed in E. coli. |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Protein Length : | His269-His417 |
Description : | Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene. Proceeds in two distinct steps. In the first half-reaction, two molecules of FPP react to form the stable presqualene diphosphate intermediate (PSQPP), with concomitant release of a proton and a molecule of inorganic diphosphate. In the second half-reaction, PSQPP undergoes heterolysis, isomerization, and reduction with NADPH or NADH to form squalene. It is the first committed enzyme of the sterol biosynthesis pathway. |
Molecular Mass : | 17.42 kDa |
Purity : | >90 % as determined by SDS-PAGE. |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name | FDFT1 farnesyl-diphosphate farnesyltransferase 1 [ Homo sapiens (human) ] |
Official Symbol | FDFT1 |
Synonyms | FDFT1; farnesyl-diphosphate farnesyltransferase 1; squalene synthase; squalene synthetase; FPP:FPP farnesyltransferase; presqualene-di-diphosphate synthase; SS; SQS; DGPT; ERG9; |
Gene ID | 2222 |
mRNA Refseq | NM_004462 |
Protein Refseq | NP_004453 |
MIM | 184420 |
UniProt ID | P37268 |
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Not For Human Consumption!
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