Recombinant Full Length Human FBXL4 Protein, GST-tagged

• Cat.No.: FBXL4-4999HF
• Product Overview: Human FBXL4 full-length ORF ( NP_036292.2, 1 a.a. - 621 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the F-box protein family, which are characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes, called SCF complexes, which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain, the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 96.5 kDa
• Protein length: 621 amino acids
• AA Sequence: MSPVFPMLTVLTMFYYICLRRRART ATRGEMMNTHRAIESNSQTSPLNAE VVQYAKEVVDFSSHYGSENSMSYTM WNLAGVPNVFPSSGDFTQTAVFRTY GTWWDQCPSASLPFKRTPPNFQSQD YVELTFEQQVYPTAVHVLETYHPGA VIRILACSANPYSPNPPAEVRWEIL WSERPTKVNASQARQFKPCIKQINF PTNLIRLEVNSSLLEYYTELDAVVL HGVKDKPVLSLKTSLIDMNDIEDDA YAEKDGCGMDSLNKKFSSAVLGEGP NNGYFDKLPYELIQLILNHLTLPDL CRLAQTCKLLSQHCCDPLQYIHLNL QPYWAKLDDTSLEFLQSRCTLVQWL NLSWTGNRGFISVAGFSRFLKVCGS ELVRLELSCSHFLNETCLEVISEMC PNLQALNLSSCDKLPPQAFNHIAKL CSLKRLVLYRTKVEQTALLSILNFC SELQHLSLGSCVMIEDYDVIASMIG AKCKKLRTLDLWRCKNITENGIAEL ASGCPLLEELDLGWCPTLQSSTGCF TRLAHQLPNLQKLFLTANRSVCDTD IDELACNCTRLQQLDILGTRMVSPA SLRKLLESCKDLSLLDVSFCSQIDN RAVLELNASFPKVFIKKSFTQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FBXL4 F-box and leucine-rich repeat protein 4 [ Homo sapiens ]
• Official Symbol: FBXL4
• Synonyms: FBXL4; F-box and leucine-rich repeat protein 4; F-box/LRR-repeat protein 4; FBL4; FBL5; F-box protein FBL4; F-box protein FBL4/FBL5
• Gene ID: 26235
• mRNA Refseq: NM_012160
• Protein Refseq: NP_036292
• MIM: 605654
• UniProt ID: Q9UKA2