FBXL4

  • Official Full Name

    F-box and leucine-rich repeat protein 4

  • Overview

    This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 9 tandem leucine-rich repeats.

  • Synonyms

    FBXL4;F-box and leucine-rich repeat protein 4;F-box/LRR-repeat protein 4;FBL4;FBL5;F box and leucine rich repeat protein 4;F box protein FBL4/FBL5;F box/LRR repeat protein 4;F-box protein FBL 4;F-box protein FBL4/FBL5;FBL 4;FBL 5;FBXL4_HUMAN;F-box protein FBL4;OTTHUMP00000016888

Recombinant Proteins

  • Rhesus macaque
  • Zebrafish
  • Human
  • Mouse
  • Mammalian Cell
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
FBXL4-1655R Recombinant Rhesus monkey FBXL4 Protein, His-tagged Mammalian Cell Rhesus macaque His
FBXL4-1707Z Recombinant Zebrafish FBXL4 Mammalian Cell Zebrafish His
FBXL4-3905H Recombinant Human FBXL4 Protein, GST-tagged Wheat Germ Human GST
FBXL4-5724M Recombinant Mouse FBXL4 Protein Mammalian Cell Mouse His
FBXL4-600HCL Recombinant Human FBXL4 cell lysate Human Non
FBXL4-1479R Recombinant Rhesus Macaque FBXL4 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
FBXL4-1479R-B Recombinant Rhesus Macaque FBXL4 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
FBXL4-3148M Recombinant Mouse FBXL4 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
FBXL4-3148M-B Recombinant Mouse FBXL4 Protein Pre-coupled Magnetic Beads HEK293 Mouse
FBXL4-4999HF Recombinant Full Length Human FBXL4 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 621 amino acids

    Involved Pathway

    FBXL4 involved in several pathways and played different roles in them. We selected most pathways FBXL4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    FBXL4 has several biochemical functions, for example, contributes_to ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXL4 itself. We selected most functions FBXL4 had, and list some proteins which have the same functions with FBXL4. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to ubiquitin protein ligase activity FBXL2,CUL3,FBXL14,SKP2,FBXL14B,CUL5A,CUL4B,MED12,CUL1A,CUL5

    Interacting Protein

    FBXL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXL4.

    nrdD;Tpx2;Nedd1;EXOSC2

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