Recombinant Full Length Human ELAVL1 Protein, GST-tagged

• Cat.No.: ELAVL1-145HF
• Product Overview: Recombinant Human ELAVL1 full-length ORF (1 a.a. - 326 a.a.) fused with GST-tag at N-terminal, was expressed in vitro Wheat germ.

Specification

• Description: ELAV-like protein 1 or HuR (human antigen R) is a protein that in humans is encoded by the ELAVL1 gene. The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It stabilizes mRNAs and thereby regulates gene expression.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 62.5 kDa
• Protein length: 1 a.a. - 326 a.a.
• AA Sequence: MSNGYEDHMA EDCRGDIGRT NLIVNYLPQN MTQDELRSLF SSIGEVESAK LIRDKVAGHS LGYGFVNYVT AKDAERAINT LNGLRLQSKT IKVSYARPSS EVIKDANLYI SGLPRTMTQK DVEDMFSRFG RIINSRVLVD QTTGLSRGVA FIRFDKRSEA EEAITSFNGH KPPGSSEPIT VKFAANPNQN KNVALLSQLY HSPARRFGGP VHHQAQRFRF SPMGVDHMSG LSGVNVPGNA SSGWCIFIYN LGQDADEGIL WQMFGPFGAV TNVKVIRDFN TNKCKGFGFV TMTNYEEAAM AIASLNGYRL GDKILQVSFK TNKSHK
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH8.0 in the elution buffer.

Gene Information

• Gene Name: ELAVL1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) [ Homo sapiens ]
• Official Symbol: ELAVL1
• Synonyms: ELAVL1; ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); HUR; Hua; MelG; ELAV1; ELAV-like protein 1; Hu antigen R; hu-antigen R; embryonic lethal, abnormal vision, drosophila, homolog-like 1
• Gene ID: 1994
• mRNA Refseq: NM_001419
• Protein Refseq: NP_001410
• MIM: 603466
• UniProt ID: Q15717

Reviews

12/19/2022

It is very pure and can be used with confidence.

07/20/2021

In enzymatic experiments, ELAVL1 was found to have high catalytic efficiency.

06/11/2020

In immunological experiments, it was found that ELAVL1 had good antigenicity and could induce target immune response.

Q&As

Is relationship between the ELAVL1 gene and the immune system?

Studies have shown that the ELAVL1 gene may be involved in the regulation of the immune system, especially in the inflammatory response.

What is the localization of the ELAVL1 gene in cells?

The protein encoded by the ELAVL1 gene is mainly located in the cytoplasm and nucleus.

What is the change in the expression level of ELAVL1 gene in tumors?

In some tumors, the expression level of ELAVL1 gene may be increased or decreased, which is related to the occurrence and progression of tumors.

What is the effect of ELAVL1 gene on apoptosis?

This gene may play an important role in the process of apoptosis, but its specific mechanism of action still needs further research.

How is the ELAVL1 gene involved in the differentiation of nerve cells?

ELAVL1 is involved in the differentiation of nerve cells by binding to and stabilizing neuronal cell-specific microRNAs.

In which tissues and organs is the ELAVL1 gene expressed?

This gene isexpressed in many tissues and organs, including the brain, heart, liver, muscles, etc.