Recombinant Full Length Human EEA1 protein, Flag-tagged

• Cat.No.: EEA1-9389HFL
• Product Overview: Recombinant Full Length Human EEA1 protein, fused with C-terminal Flag tag, was expressed in mamanlian cells.

Specification

• Source: Mamanlian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 162.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Shipping: The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Gene Information

• Gene Name: EEA1 early endosome antigen 1 [ Homo sapiens ]
• Official Symbol: EEA1
• Synonyms: EEA1; early endosome antigen 1; early endosome antigen 1, 162kD; ZFYVE2; endosome-associated protein p162; early endosome-associated protein; zinc finger FYVE domain-containing protein 2; MST105; MSTP105
• Gene ID: 8411
• mRNA Refseq: NM_003566
• Protein Refseq: NP_003557
• MIM: 605070
• UniProt ID: Q15075

Reviews

10/04/2020

In protein electron microscopy structure analysis, the EEA1 protein demonstrates outstanding performance.

09/25/2020

the EEA1 protein's versatility allows it to be effectively employed in various experimental designs, further enhancing its suitability for diverse research needs.

02/09/2020

Their extensive knowledge and expertise can help troubleshoot issues or provide guidance on experimental design, enabling you to overcome obstacles and achieve your research goals.

Q&As

How does EEA1 protein relate to neurodegenerative disorders?

EEA1 protein has been implicated in the pathogenesis of neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease, where abnormal endosome trafficking may contribute to disease progression.

Are there any diagnostic applications of EEA1 protein in neurodegenerative disorders?

EEA1 protein expression and localization may serve as a potential diagnostic marker for certain neurodegenerative disorders, offering insights into disease pathology.

Can targeting EEA1 protein offer potential therapeutic avenues for neurodegenerative disorders?

Research suggests that modulating EEA1 protein function may hold promise as a therapeutic approach for neurodegenerative disorders, although further investigation is needed.

How does EEA1 protein function in infectious diseases?

EEA1 protein plays a critical role in the intracellular trafficking of pathogens, including viruses and bacteria, and its dysregulation can impact the outcome of infectious diseases.

How is EEA1 protein expressed in cancer cells?

In cancer cells, EEA1 protein expression levels can be altered, leading to abnormal endosome trafficking and potential implications for tumor growth and metastasis.