Recombinant Human EEA1 protein, His-tagged

• Cat.No.: EEA1-3902H
• Product Overview: Recombinant Human EEA1(His1232~Lys1348) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: EEA1 played an important role in many functions.
• Source: E. coli
• Species: Human
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300
• Molecular Mass: 17.0kDa
• Protein length: His1232~Lys1348
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: EEA1 early endosome antigen 1 [ Homo sapiens ]
• Official Symbol: EEA1
• Synonyms: EEA1; early endosome antigen 1; early endosome antigen 1, 162kD; ZFYVE2; endosome-associated protein p162; early endosome-associated protein; zinc finger FYVE domain-containing protein 2; MST105; MSTP105
• Gene ID: 8411
• mRNA Refseq: NM_003566
• Protein Refseq: NP_003557
• MIM: 605070
• UniProt ID: Q15075

Reviews

10/04/2020

In protein electron microscopy structure analysis, the EEA1 protein demonstrates outstanding performance.

09/25/2020

the EEA1 protein's versatility allows it to be effectively employed in various experimental designs, further enhancing its suitability for diverse research needs.

02/09/2020

Their extensive knowledge and expertise can help troubleshoot issues or provide guidance on experimental design, enabling you to overcome obstacles and achieve your research goals.

Q&As

How does EEA1 protein relate to neurodegenerative disorders?

EEA1 protein has been implicated in the pathogenesis of neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease, where abnormal endosome trafficking may contribute to disease progression.

Are there any diagnostic applications of EEA1 protein in neurodegenerative disorders?

EEA1 protein expression and localization may serve as a potential diagnostic marker for certain neurodegenerative disorders, offering insights into disease pathology.

Can targeting EEA1 protein offer potential therapeutic avenues for neurodegenerative disorders?

Research suggests that modulating EEA1 protein function may hold promise as a therapeutic approach for neurodegenerative disorders, although further investigation is needed.

How does EEA1 protein function in infectious diseases?

EEA1 protein plays a critical role in the intracellular trafficking of pathogens, including viruses and bacteria, and its dysregulation can impact the outcome of infectious diseases.

How is EEA1 protein expressed in cancer cells?

In cancer cells, EEA1 protein expression levels can be altered, leading to abnormal endosome trafficking and potential implications for tumor growth and metastasis.