Recombinant Full Length Human EDN1 Protein, GST-tagged

• Cat.No.: EDN1-656HF
• Product Overview: Recombinant full length Human EDN1(1 a.a. - 212 a.a) fused with GST tag at N-terminal was expressed in Wheat Germ.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Tag: GST
• Protein Length: 212 amino acids
• Description: This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.
• Form: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 50.8 kDa
• AA Sequence: MDYLLMIFSL LFVACQGAPE TAVLGAELSA VGENGGEKPT PSPPWRLRRS KRCSCSSLMD KECVYFCHLD IIWVNTPEHV VPYGLGSPRS KRALENLLPT KATDRENRCQ CASQKDKKCW NFCQAGKELR AEDIMEKDWN NHKKGKDCSK LGKKCIYQQL VRGRKIRRSS EEHLRQTRSE TMRNSVKSSF HDPKLKGNPS RERYVTHNRA HW
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: EDN1 endothelin 1 [ Homo sapiens ]
• Official Symbol: EDN1
• Synonyms: EDN1; endothelin 1; endothelin-1; ET1; preproendothelin-1; PPET1; HDLCQ7
• Gene ID: 1906
• mRNA Refseq: NM_001168319
• Protein Refseq: NP_001161791
• MIM: 131240
• UniProt ID: P05305