Recombinant Full Length Human DEDD Protein, GST-tagged

• Cat.No.: DEDD-2416HF
• Product Overview: Human DEDD full-length ORF ( NP_001034800.1, 1 a.a. - 318 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 63.2 kDa
• Protein length: 318 amino acids
• AA Sequence: MAGLKRRASQVWPEEHGEQEHGLYS LHRMFDIVGTHLTHRDVRVLSFLFV DVIDDHERGLIRNGRDFLLALERQG RCDESNFRQVLQLLRIITRHDLLPY VTLKRRRAVCPDLVDKYLEETSIRY VTPRALSDPEPRPPQPSKTVPPHYP VVCCPTSGPQMCSKRPARGRATLGS QRKRRKSVTPDPKEKQTCDIRLRVR AEYCQHETALQGNVFSNKQDPLERQ FERFNQANTILKSRDLGSIICDIKF SELTYLDAFWRDYINGSLLEALKGV FITDSLKQAVGHEAIKLLVNVDEED YELGRQKLLRNLMLQALP
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DEDD death effector domain containing [ Homo sapiens ]
• Official Symbol: DEDD
• Synonyms: DEDD; death effector domain containing; death effector domain-containing protein; CASP8IP1; DEDD1; DEFT; FLDED1; KE05; DEDPro1; FLDED-1; death effector domain-containing testicular molecule
• Gene ID: 9191
• mRNA Refseq: NM_001039711
• Protein Refseq: NP_001034800
• MIM: 606841
• UniProt ID: O75618