DEDD
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Official Full Name
death effector domain containing -
Overview
This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. -
Synonyms
DEDD;death effector domain containing;death effector domain-containing protein;CASP8IP1;DEDD1;DEFT;FLDED1;KE05;Death effector domain containing protein;Death effector domain containing testicular molecule;DEDD 1;DEDPro 1;DEDPro1;FLDED 1;KE 05;OTTHUMP00000031822;FLDED-1;OTTHUMP00000031821;death effector domain-containing testicular molecule
Recombinant Proteins
- Rhesus macaque
- Rat
- Human
- Zebrafish
- Mammalian Cell
- Wheat Germ
- E.coli
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
Involved Pathway
DEDD involved in several pathways and played different roles in them. We selected most pathways DEDD participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DEDD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
DEDD has several biochemical functions, for example, DNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DEDD itself. We selected most functions DEDD had, and list some proteins which have the same functions with DEDD. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PRDM7,RGR,SBDS,TRP53,NFE2L3,CC2D1B,LAIR1,RAB33A,HNRNPF,FAM168A |
| DNA binding | TFAP4,RFX1A,ZNF624,SYCP1,TBX22,ADNPA,HIST2H2L,ZFP511,ZBTB24,GTF2F2B |
Interacting Protein
DEDD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DEDD here. Most of them are supplied by our site. Hope this information will be useful for your research of DEDD.
APLP2;C7orf28A;PAM;ARID4A;ATP6V1E1;KHK;SMAD3;TCEAL5;RSRC2;ABCA9;USP7;LTV1;SERPINI1;RANBP3;CCDC59;USP22;SHMT1;BATF2
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References
