Recombinant Full Length Human CXCR5 Protein, GST-tagged

• Cat.No.: CXCR5-111HF
• Product Overview: Recombinant human CXCR5 full-length ORF ( NP_001707.1, 1 a.a. - 372 a.a.) protein, fused to GST-tag at N-terminus, was expressed in vitro wheat germ expression system. Purified by Glutathione Sepharose 4 Fast Flow

Specification

• Description: This gene was identified as a gene specifically expressed in Burkitt''s lymphoma and lymphatic tissues. The protein encoded by this gene is predicted to be a seven transmembrane G protein- coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B-lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of this gene and its mouse conterpart strongly suggest the essential function of this gene in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen. Two alternatively spliced variants of this gene exist.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 68.4kDa
• Protein length: 1-372aa
• AA Sequence: MNYPLTLEMD LENLEDLFWE LDRLDNYNDT SLVENHLCPA TEGPLMASFK AVFVPVAYSL IFLLGVIGNV LVLVILERHR QTRSSTETFL FHLAVADLLL VFILPFAVAE GSVGWVLGTF LCKTVIALHK VNFYCSSLLL ACIAVDRYLA IVHAVHAYRH RRLLSIHITC GTIWLVGFLL ALPEILFAKV SQGHHNNSLP RCTFSQENQA ETHAWFTSRF LYHVAGFLLP MLVMGWCYVG VVHRLRQAQR RPQRQKAVRV AILVTSIFFL CWSPYHIVIF LDTLARLKAV DNTCKLNGSL PVAITMCEFL GLAHCCLNPM LYTFAGVKFR SDLSRLLTKL GCTGPASLCQ LFPSWRRSSL SESENATSLT TF
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CXCR5 chemokine (C-X-C motif) receptor 5 [ Homo sapiens ]
• Official Symbol: CXCR5
• Synonyms: CXCR5; chemokine (C-X-C motif) receptor 5; BLR1, Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C X C motif) receptor 5) , Burkitt lymphoma receptor 1, GTP binding protein; C-X-C chemokine receptor type 5; CD185; MDR15; CXC-R5; CXCR-5; MDR-15; monocyte-derived receptor 15; Burkitt lymphoma receptor 1, GTP-binding protein; Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5); BLR1; MGC117347
• Gene ID: 643
• mRNA Refseq: NM_001716
• Protein Refseq: NP_001707
• MIM: 601613
• UniProt ID: P32302