Recombinant Full Length Human ARHGEF2 Protein, GST-tagged

• Cat.No.: ARHGEF2-1103HF
• Product Overview: Human ARHGEF2 full-length ORF ( AAH20567, 1 a.a. - 959 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Tag: GST
• Protein Length: 959 amino acids
• Description: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009]
• Molecular Mass: 131.12 kDa
• AA Sequence: MKEAKDARYT NGHLFTTISV SGMTMCYACN KSITAKEALI CPTCNVTIHN RCKDTLANCT KVKQKQQKAA LLKNNTALQS VSLRSKTTIR ERPSSAIYPS DSFRQSLLGS RRGRSSLSLA KSVSTTNIAG HFNDESPLGL RRILSQSTDS LNMRNRTLSV ESLIDEAEVI YSELMSDFEM DEKDFAADSW SLAVDSSFLQ QHKKEVMKQQ DVIYELIQTE LHHVRTLKIM TRLFRTGMLE ELHLEPGVVQ GLFPCVDELS DIHTRFLSQL LERRRQALCP GSTRNFVIHR LGDLLISQFS GPSAEQMCKT YSEFCSRHSK ALKLYKELYA RDKRFQQFIR KVTRPAVLKR HGVQECILLV TQRITKYPLL ISRILQHSHG IEEERQDLTT ALGLVKELLS NVDEGIYQLE KGARLQEIYN RMDPRAQTPV PGKGPFGREE LLRRKLIHDG CLLWKTATGR FKDVLVLLMT DVLVFLQEKD QKYIFPTLDK PSVVSLQNLI VRDIANQEKG MFLISAAPPE MYEVHTASRD DRSTWIRVIQ QSVRTCPSRE DFPLIETEDE AYLRRIKMEL QQKDRALVEL LREKVGLFAE MTHFQAEEDG GSGMALPTLP RGLFRSESLE SPRGERLLQD AIREVEGLKD LLVGPGVELL LTPREPALPL EPDSGGNTSP GVTANGEART FNGSIELCRA DSDSSQRDRN GNQLRSPQEE ALQRLVNLYG LLHGLQAAVA QQDTLMEARF PEGPERREKL CRANSRDGEA GRAGAAPVAP EKQATELALL QRQHALLQEE LRRCRRLGEE RATEAGSLEA RLRESEQARA LLEREAEEAR RQLAALGQTE PLPAEAPWAR RPVDPRRRSL PAGDALYLSF NPPQPSRGTD RLDLPVTTRS VHRNFEDRER QELGSPEERL QDSSDPDTGS EEEGSSRLSP PHSPRDFTRM QDIPEETESR DGEAVASES
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 [ Homo sapiens ]
• Official Symbol: ARHGEF2
• Synonyms: ARHGEF2; Rho/Rac guanine nucleotide exchange factor (GEF) 2; rho/rac guanine nucleotide exchange factor (GEF) 2; rho guanine nucleotide exchange factor 2; GEF H1; KIAA0651; LFP40; P40; microtubule-regulated Rho-GEF; guanine nucleotide exchange factor H1; proliferating cell nucleolar antigen p40; Rho/Rac guanine nucleotide exchange factor 2; GEF; GEFH1; GEF-H1; FLJ45440; DKFZp547L106; DKFZp547P1516
• Gene ID: 9181
• mRNA Refseq: NM_001162383
• Protein Refseq: NP_001155855
• MIM: 607560
• UniProt ID: Q92974