Recombinant Full Length Human AP1B1 Protein, GST-tagged

• Cat.No.: AP1B1-1013HF
• Product Overview: Human AP1B1 full-length ORF ( CAK54367.1, 1 a.a. - 939 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 129.69 kDa
• Protein length: 939 amino acids
• AA Sequence: MTDSKYFTTT KKGEIFELKA ELNSDKKEKK KEAVKKVIAS MTVGKDVSAL FPDVVNCMQT DNLELKKLVY LYLMNYAKSQ PDMAIMAVNT FVKDCEDPNP LIRALAVRTM GCIRVDKITE YLCEPLRKCL KDEDPYVRKT AAVCVAKLHD INAQLVEDQG FLDTLKDLIS DSNPMVVANA VAALSEIAES HPSSNLLDLN PQSINKLLTA LNECTEWGQI FILDCLANYM PKDDREAQSI CERVTPRLSH ANSAVVLSAV KVLMKFMEML SKDLDYYGTL LKKLAPPLVT LLSAEPELQY VALRNINLIV QKRPEILKHE MKVFFVKYND PIYVKLEKLD IMIRLASQAN IAQVLAELKE YATEVDVDFV RKAVRAIGRC AIKVEQSAER CVSTLLDLIQ TKVNYVVQEA IVVIKDIFRK YPNKYESVIA TLCENLDSLD EPEARAAMIW IVGEYAERID NADELLESFL EGFHDESTQV QLQLLTAIVK LFLKKPTETQ ELVQQVLSLA TQDSDNPDLR DRGYIYWRLL STDPVAAKEV VLAEKPLISE ETDLIEPTLL DELICYIGTL ASVYHKPPSA FVEGGRGVVH KSLPPRTASS ESAESPETAP TGAPPGEQPD VIPAQGDLLG DLLNLDLGPP VSGPPLATSS VQMGAVDLLG GGLDSLIGGT NFVAPPTAAV PANLGAPIGS GLSDLFDLTS GVGTLSGSYV APKAVWLPAM KAKGLEISGT FTRQVGSISM DLQLTNKALQ VMTDFAIQFN RNSFGLAPAA PLQVHAPLSP NQTVEISLPL STVGSVMKME PLNNLQVAVK NNIDVFYFST LYPLHILFVE DGKMDRQMFL ATWKDIPNEN EAQFQIRDCP LNAEAASSKL QSSNIFTVAK RNVEGQDMLY QSLKLTNGIW VLAELRIQPG NPSCTLSLKC RAPEVSQHVY QAYETILKN
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: AP1B1 adaptor-related protein complex 1, beta 1 subunit [ Homo sapiens ]
• Official Symbol: AP1B1
• Synonyms: AP1B1; adaptor-related protein complex 1, beta 1 subunit; ADTB1, CLAPB2; AP-1 complex subunit beta-1; AP105A; BAM22; beta1-adaptin; beta-1-adaptin; beta-adaptin 1; beta-prime-adaptin; Golgi adaptor HA1/AP1 adaptin beta subunit; adaptor protein complex AP-1 subunit beta-1; adapter-related protein complex 1 subunit beta-1; clathrin assembly protein complex 1 beta large chain; plasma membrane adaptor HA2/AP2 adaptor beta subunit; ADTB1; CLAPB2
• Gene ID: 162
• mRNA Refseq: NM_001127
• Protein Refseq: NP_001118
• MIM: 600157
• UniProt ID: Q10567