Recombinant Human AP1B1 Protein, MYC/DDK-tagged

• Cat.No.: AP1B1-2318H
• Product Overview: Recombinant human AP1B1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Description: Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 104.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: AP1B1 adaptor-related protein complex 1, beta 1 subunit [ Homo sapiens ]
• Official Symbol: AP1B1
• Synonyms: ADTB1; AP105A; BAM22; CLAPB2
• Gene ID: 162
• mRNA Refseq: NM_001127
• Protein Refseq: NP_001118
• MIM: 600157
• UniProt ID: Q10567