AP1B1

  • Official Full Name

    adaptor-related protein complex 1, beta 1 subunit
  • Overview

    Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants.
  • Synonyms

    AP1B1;adaptor-related protein complex 1, beta 1 subunit;ADTB1, CLAPB2;AP-1 complex subunit beta-1;AP105A;BAM22;beta1-adaptin;beta-1-adaptin;beta-adaptin 1;beta-prime-adaptin;Golgi adaptor HA1/AP1 adaptin beta subunit;adaptor protein complex AP-

Recombinant Proteins

  • Human
  • Rat
  • Zebrafish
  • Mouse
  • E.coli
  • E.Coli/Yeast
  • Wheat Germ
  • Mammalian Cells
  • In Vitro Cell Free System
  • HEK293
  • His
  • GST
  • DDK
  • Myc
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
AP1B1-9707H Recombinant Human AP1B1, His-tagged E.coli Human His 671-919a.a.
Ap1b1-3523R Recombinant Rat Ap1b1, His-tagged E.Coli/Yeast Rat His 949
AP1B1-644H Recombinant Human AP1B1 protein, GST-tagged Wheat Germ Human GST
AP1B1-6919Z Recombinant Zebrafish AP1B1 Mammalian Cells Zebrafish His
AP1B1-698R Recombinant Rat AP1B1 Protein Mammalian Cells Rat His
AP1B1-1013HF Recombinant Full Length Human AP1B1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 939 amino acids
AP1B1-1261H Recombinant Human AP1B1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
AP1B1-178H Recombinant Human AP1B1 Protein, His-tagged E.coli Human His Thr2-Val255
AP1B1-2318H Recombinant Human AP1B1 Protein, MYC/DDK-tagged HEK293 Human DDK&Myc
AP1B1-354R Recombinant Rat AP1B1 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
AP1B1-354R-B Recombinant Rat AP1B1 Protein Pre-coupled Magnetic Beads HEK293 Rat
AP1B1-4359H Recombinant Human AP1B1 protein, His&Myc-tagged E.coli Human His&Myc 1-584aa
AP1B1-4360H Recombinant Human AP1B1 protein, His&Myc-tagged E.coli Human His&Myc 1-584aa
Ap1b1-618M Recombinant Mouse Ap1b1 Protein, MYC/DDK-tagged HEK293 Mouse DDK&Myc

    Involved Pathway

    AP1B1 involved in several pathways and played different roles in them. We selected most pathways AP1B1 participated on our site, such as Adaptive Immune System,Clathrin derived vesicle budding,Disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP1B1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Immune System SPSB4,MAP3K8,CLEC2B,CHST13,FCN2,GRAP2B,ARIH2,ARIH1L,PIK3AP1,EIF4G2
    HIV Infection AP1G1,TCEB3,NMT1,PSTPIP2,NPM1,PACS1,PSIP1,PDCD6IP,SSRP1,CDK9
    Clathrin derived vesicle budding SNX9A,BLOC1S6,PUM1,CLTA,AP1M2,SNX9B,PICALMA,YIPF6,GAK,CLVS2
    Disease CDC37,CHMP4B,HDAC5,KREMEN1,RDBP,CCDC59,FDX1,MYO18A,RCC1,VPS37A
    FOXA1 transcription factor network NFIC,NR2F2,NRIP1,CEBPB,POU2F1,CYP2C18,NFIB,DSCAM,FOXA1,CC10
    Adaptive Immune System RAET1E,CD200R2,RNF220,CSK,ERAP2,RNF14,KLC3,TRIM63,CYBA,UBR1
    Golgi Associated Vesicle Biogenesis TPD52L1,DTNBP1,HIP1RB,AP1S1,SNX9B,DTNBP1B,YIPF6,AP3S1,GAK,CPD
    Host Interactions of HIV factors AP1S1,PACS1,AP1M2,AP1G1,PSIP1,PPIAL4A,APOBEC3G,DOCK2,RCC1

    Protein Function

    AP1B1 has several biochemical functions, for example, protein binding,protein kinase binding,protein transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AP1B1 itself. We selected most functions AP1B1 had, and list some proteins which have the same functions with AP1B1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding PTPRA,UBQLN4,ULK3,IGBP1,UBE2N,DNAJB1,CIB4,USP47,PAIP2,THAP8
    transporter activity CPNE1,FABP7,XPO1,RBP7,RBP7B,CSN1S1,NUP155,ABCB8,APODB,RLBP1
    protein transporter activity TIMM10,ARFGAP3,SOSTDC1B,C11orf73,COG2,TIMM9,VPS26BL,AP2S1,CALCRL,XPO5
    protein kinase binding BCL10,NEK6,CD36,SLC12A4,FAF1,LAX1,GPRC5B,ATG13,MAG,RFFL

    Interacting Protein

    AP1B1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP1B1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP1B1.

    Ap1g1;Ap1m1;nef;AP1S1;AP1S3;1-phosphatidyl-1d-myo-inositol 3,4,5-trisphosphate

    Resources

    References

    • Saito, T; Ji, G; et al. Genetic variations in humans associated with differences in the course of hepatitis C. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 317:335-341(2004).

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