Recombinant Full Length Human ANKHD1 Protein, GST-tagged

• Cat.No.: ANKHD1-1214HF
• Product Overview: Human ANKHD1 full-length ORF ( NP_078944.2, 1 a.a. - 627 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought to function as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play an antiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of which generates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting in a protein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments. [provided by RefSeq, Sep 2010]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 91.3 kDa
• Protein length: 627 amino acids
• AA Sequence: MLTDSGGGGT SFEEDLDSVA PRSAPAGASE PPPPGGVGLG IRTVRLFGEA GPASGVGSSG GGGSGSGTGG GDAALDFKLA AAVLRTGGGG GASGSDEDEV SEVESFILDQ EDLDNPVLKT TSEIFLSSTA EGADLRTVDP ETQARLEALL EAAGIGKLST ADGKAFADPE VLRRLTSSVS CALDEAAAAL TRMKAENSHN AGQVDTRSLA EACSDGDVNA VRKLLDEGRS VNEHTEEGES LLCLACSAGY YELAQVLLAM HANVEDRGNK GDITPLMAAS SGGYLDIVKL LLLHDADVNS QSATGNTALT YACAGGFVDI VKVLLNEGAN IEDHNENGHT PLMEAASAGH VEVARVLLDH GAGINTHSNE FKESALTLAC YKGHLDMVRF LLEAGADQEH KTDEMHTALM EACMDGHVEV ARLLLDSGAQ VNMPADSFES PLTLAACGGH VELAALLIER GANLEEVNDE GYTPLMEAAR EGHEEMVALL LAQGANINAQ TEETQETALT LACCGGFSEV ADFLIKAGAD IELGCSTPLM EASQEGHLEL VKYLLASGAN VHATTATGDT ALTYACENGH TDVADVLLQA GADLDKQEDM KTILEGIDPA KHQVRVAFDA CKLLRKE
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ANKHD1 ankyrin repeat and KH domain containing 1 [ Homo sapiens ]
• Official Symbol: ANKHD1
• Synonyms: ANKHD1; ankyrin repeat and KH domain containing 1; ankyrin repeat and KH domain-containing protein 1; FLJ10042; FLJ11979; FLJ14127; FLJ20288; KIAA1085; MASK; HIV-1 Vpr-binding ankyrin repeat protein; multiple ankyrin repeats, single KH-domain homolog; VBARP; PP2500
• Gene ID: 54882
• mRNA Refseq: NM_001197030
• Protein Refseq: NP_001183959
• MIM: 610500
• UniProt ID: Q8IWZ3