Recombinant Full Length Human AHRR Protein, GST-tagged

• Cat.No.: AHRR-950HF
• Product Overview: Human AHRR full-length ORF ( AAI60162.1, 1 a.a. - 719 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Tag: GST
• Protein Length: 719 amino acids
• Description: The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011]
• Molecular Mass: 79.1 kDa
• AA Sequence: MPRTMIPPGE CTYAGRKRRR PLQKQRPAVG AEKSNPSKRH RDRLNAELDH LASLLPFPPD IISKLDKLSV LRLSVSYLRV KSFFQVVQEQ SSRQPAAGAP SPGDSCPLAG SAVLEGRLLL ESLNGFALVV SAEGTIFYAS ATIVDYLGFH QTDVMHQNIY DYIHVDDRQD FCRQLHWAMD PPQVVFGQPP PLETGDDAIL GRLLRAQEWG TGTPTEYSAF LTRCFICRVR CLLDSTSGFL ARGSQAWQLR LCCPEPLMTM QFQGKLKFLF GQKKKAPSGA MLPPRLSLFC IAAPVLLPSA AEMKMRSALL RAKPRADTAA TADAKVKATT SLCESELHGK PNYSAGRSSR ESGVLVLREQ TDAGRWAQVP ARAPCLCLRG GPDLVLDPKG GSGDREEEQH RMLSRASGVT GRRETPGPTK PLPWTAGKHS EDGARPRLQP SKNDPPSLRP MPRGSCLPCP CVQGTFRNSP ISHPPSPSPS AYSSRTSRPM RDVGEDQVHP PLCHFPQRSL QHQLPQPGAQ RFATRGYPME DMKLQGVPMP PGDLCGPTLL LDVSIKMEKD SGCEGAADGC VPSQVWLGAS DRSHPATFPT RMHLKTEPDS RQQVYISHLG HGVRGAQPHG RATAGRSREL TPFHPAHCAC LEPTDGLPQS EPPHQLCARG RGEQSCTCRA AEAAPVVKRE PLDSPQWATH SQGMVPGMLP KSALATLVPP QASGCTFLP
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: AHRR aryl-hydrocarbon receptor repressor [ Homo sapiens ]
• Official Symbol: AHRR
• Synonyms: AHRR; aryl-hydrocarbon receptor repressor; AHH, AHHR, aryl hydrocarbon receptor regulator; aryl hydrocarbon receptor repressor; bHLHe77; KIAA1234; ahR repressor; dioxin receptor repressor; aryl hydrocarbon hydroxylase regulator; class E basic helix-loop-helix protein 77; AHH; AHHR; MGC167813; MGC176630
• Gene ID: 57491
• mRNA Refseq: NM_001242412
• Protein Refseq: NP_001229341
• MIM: 606517
• UniProt ID: A9YTQ3