Recombinant Full Length Human AGAP2 Protein, GST-tagged

• Cat.No.: AGAP2-995HF
• Product Overview: Human AGAP2 full-length ORF ( AAH28020.1, 1 a.a. - 836 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 116.9 kDa
• Protein length: 836 amino acids
• AA Sequence: MHAQRQFVVA AVRAEVRRHE VAKQALNRLR KLAERVDDPE LQDSIQASLD SIREAVINSQ EWTLSRSIPE LRLGVLGDAR SGKSSLIHRF LTGSYQVLEK TESEQYKKEM LVDGQTHLVL IREEAGAPDA KFSGWADAVI FVFSLEDENS FQAVSRLHGQ LSSLRGEGRG GLALALVGTQ DRISASSPRV VGDARARALC ADMKRCSYYE TCATYGLNVD RVFQEVAQKV VTLRKQQQLL AACKSLPSSP SHSAASTPVA GQASNGGHTS DYSSSLPSSP NVGHRELRAE AAAVAGLSTP GSLHRAAKRR TSLFANRRGS DSEKRSLDSR GETTGSGRAI PIKQSFLLKR SGNSLNKEWK KKYVTLSSNG FLLYHPSIND YIHSTHGKEM DLLRTTVKVP GKRPPRAISA FGPSASINGL VKDMSTVQMG EGLEATTPMP SPSPSPSSLQ PPPDQTSKHL LKPDRNLARA LSTDCTPSGD LSPLSREPPP SPMVKKQRRK KLTTPSKTEG SAGQAEEENF EFLIVSSTGQ TWHFEAASFE ERDAWVQAIE SQILASLQCC ESSKVKLRTD SQSEAVAIQA IRNAKGNSIC VDCGAPNPTW ASLNLGALIC IECSGIHRNL GTHLSRVRSL DLDDWPRELT LVLTAIGNDT ANRVWESDTR GRAKPSRDSS REERESWIRA KYEQLLFLAP LSTSEEPLGR QLWAAVQAQD VATVLLLLAH ARHGPLDTSV EDPQLRSPLH LAAELAHVVI TQLLLWYGAD VAARDAQGRT ALFYARQAGS QLCADILLQH GCPGEGGSAA TTPSAATTPS ITATPSPRRR SSAASVGRAD APVALV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 [ Homo sapiens ]
• Official Symbol: AGAP2
• Synonyms: AGAP2; ArfGAP with GTPase domain, ankyrin repeat and PH domain 2; centaurin, gamma 1, CENTG1; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2; cnt-g1; centaurin, gamma 1; phosphoinositide 3-kinase enhancer; phosphatidylinositol 3-kinase enhancer; phosphatidylinositol-3-kinase enhancer; GTP-binding and GTPase activating protein 2; Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 2; PIKE; GGAP2; CENTG1; FLJ16430; KIAA0167
• Gene ID: 116986
• mRNA Refseq: NM_001122772
• Protein Refseq: NP_001116244
• MIM: 605476
• UniProt ID: Q99490