Recombinant Full Length Human ADAMTS18 Protein, GST-tagged

• Cat.No.: ADAMTS18-918HF
• Product Overview: Human ADAMTS18 full-length ORF (BAD18550.1, 1 a.a. - 415 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Tag: GST
• Protein Length: 415 amino acids
• Description: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may regulate hemostatic balance and function as a tumor suppressor. Mutations in this gene may be associated with microcornea, myopic chorioretinal atrophy, and telecanthus (MMCAT) and cone-rod dystrophy in human patients. [provided by RefSeq, May 2016]
• Molecular Mass: 72.2 kDa
• AA Sequence: MVAYSVQVLA VFISCAILTL AMKIAWIFGL NSVQNITANL SVDGSTSGNP IQKWKRKIDA NCTARLRTLN FFFAMSGKVK DGTPCSPNKN DVCIDGVCEL VGCDHELGSK AVSDACGVCK GDNSTCKFYK GLYLNQHKAN EYYPVVLIPA GARSIEIQEL QVSSSYLAVR SLSQKHYLTG GWSIDWPGEF PFAGTTFEYQ RSFNRPERLY APGPTNETLV FEILMQGKNP GIAWKYALPK VMNGTPPATK RPAYTWSIVQ SECSVSCGGG YINVKAICLR DQNTQVNSSF CSAKTKPVTE PKICNRRACP AHPVYNMVAG WYSLPWQQCT VTCGGGVQTR SVHCVQQGRP SSSCLLHQKP PVLRACNTNF CPAPEKREDP SCVDFFNWCH LVPQHGVCNH KFYGKQCCKS CTRKI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 [ Homo sapiens ]
• Official Symbol: ADAMTS18
• Synonyms: ADAMTS18; ADAM metallopeptidase with thrombospondin type 1 motif, 18; a disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 18 , ADAMTS21; A disintegrin and metalloproteinase with thrombospondin motifs 18; disintegrin and metalloprotease-like protein; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 18; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 21; KNO2; ADAMTS21
• Gene ID: 170692
• mRNA Refseq: NM_199355
• Protein Refseq: NP_955387
• MIM: 607512
• UniProt ID: Q8TE60