Recombinant Cynomolgus IL20RB Protein, Fc-tagged

• Cat.No.: IL20RB-447C
• Product Overview: Recombinant Cynomolgus IL20RB (XP_005545913.1) (Asp30-Ala230) was expressed with the Fc region of human IgG1 at the C-terminus.

Specification

• Species: Cynomolgus
• Source: HEK293
• Tag: Fc
• Protein Length: Asp30-Ala230
• Description: IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically ass centigradeiated with a tyrosine kinase belonging to the Janus kinase (JAK) family. IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20.
• Predicted N Terminal: Asp 30
• Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 %- 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Molecular Mass: The recombinant cynomolgus IL20RB consists of 439 amino acids and predicts a molecular mass of 49.2 kDa.
• Endotoxin: < 1.0 EU per μg protein as determined by the LAL method.
• Purity: > 90 % as determined by SDS-PAGE.
• Storage: Samples are stable for up to twelve months from date of receipt at-70 centigrade. Store it under sterile conditions at-20 centigrade to-80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Official Symbol: IL20RB
• Synonyms: IL20RB;interleukin 20 receptor subunit beta;interleukin-20 receptor subunit beta;interleukin 20 receptor beta