Recombinant Cynomolgus DDR2 Protein, His-tagged

• Cat.No.: DDR2-118C
• Product Overview: Recombinant Cynomolgus DDR2 protein with a His-tag was expressed in HEK293

Specification

• Species: Cynomolgus
• Source: HEK293
• Tag: His
• Protein Length: 1-399 aa
• Description: This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia.
• Molecular Mass: The protein has a calculated MW of 43 kDa.
• AA Sequence: QVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSGALPTSPMTPTTYDPMLKIDDSNTRHHHHHH
• Endotoxin: <1 EU/μg
• Purity: >90% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 1.97 mg/mL
• Storage Buffer: PBS, pH7.4

Gene Information

• Gene Name: DDR2 discoidin domain receptor tyrosine kinase 2 [ Macaca mulatta (Rhesus monkey) ]
• Official Symbol: DDR2
• Synonyms: DDR2; discoidin domain receptor tyrosine kinase 2; discoidin domain-containing receptor 2; EC 2.7.10.1
• Gene ID: 720124
• mRNA Refseq: XM_028826657
• Protein Refseq: XP_028682490
• UniProt ID: A0A5F8A058