Recombinant COVID-19 NSP3 protein, His-tagged
Cat.No. : | NSP3-81V |
Product Overview : | Recombinant COVID-19 NSP3 full length or partial length protein was fused to His-tag and expressed in HEK293. |
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Species : | Sars-CoV-2 |
Source : | HEK293 |
Tag : | His |
Description : | Responsible for the cleavages located at the N-terminus of the replicase polyprotein. In addition, PL-PRO possesses a deubiquitinating/deISGylating activity and processes both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains from cellular substrates. Participates together with nsp4 in the assembly of virally-induced cytoplasmic double-membrane vesicles necessary for viral replication. Antagonizes innate immune induction of type I interferon by blocking the phosphorylation, dimerization and subsequent nuclear translocation of host IRF3. Prevents also host NF-kappa-B signaling. |
Form : | PBS, pH7.4. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Storage : | Store it at 4 ºC for short time. For long term storage, store it at -20ºC to -80ºC. |
Warning : | For Research Use Only. |
Gene Name | orf1ab |
Official Symbol | orf1ab |
Synonyms | pp1ab |
Gene ID | 1489680 |
Protein Refseq | NP_828862.2 |
UniProt ID | P0C6X7 |
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Not For Human Consumption!
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