Recombinant il1a Proteins
- Product List
- Specification
- Gene Information
- Cat. #
- Tag
- Source (Host)
- Species
- Protein Length
- Price
- Datasheet
Description : | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimers disease. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-271a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name | IL1A interleukin 1, alpha [ Homo sapiens ] |
Official Symbol | IL1A |
Synonyms | IL1A; interleukin 1, alpha; IL1; interleukin-1 alpha; hematopoietin 1; IL 1A; IL1 ALPHA; IL1F1; preinterleukin 1 alpha; pro interleukin 1 alpha; IL-1 alpha; hematopoietin-1; pro-interleukin-1-alpha; IL-1A; IL1-ALPHA; |
Gene ID | 3552 |
mRNA Refseq | NM_000575 |
Protein Refseq | NP_000566 |
MIM | 147760 |
UniProt ID | P01583 |
Chromosome Location | 2q14 |
Pathway | Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytokines and Inflammatory Response, organism-specific biosystem; FAS pathway and Stress induction of HSP regulation, organism-specific biosystem; |
Function | copper ion binding; cytokine activity; interleukin-1 receptor binding; protein binding; |