Recombinant C. difficile tcdB Protein
Cat.No. : | tcdB-007C |
Product Overview : | Recombinant Clostridioides difficile tcdB protein without tag was expressed in E.coli |
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Species : | C.difficile |
Source : | E.coli |
Description : | Toxin B from Clostridium difficile, also known as TcdB, is a cytotoxin that has glucosyltransferase and cysteine protease activities. It inactivates host Rho family GTPases by glucosylation, altering cytoskeletal structure, cell division, and cell-cell adhesion. Toxin B can induce activation of the inflammasome and apoptosis. While both toxin A and toxin B inactivate Rho family GTPases, toxin B more potently induces mammalian cell rounding in culture. |
Purity : | ≥90% estimated by SDS-PAGE |
Stability : | ≥ 2 years |
Storage : | 2 to 8 centigrade |
Concentration : | 0.2 mg/ml |
Storage Buffer : | Each vial contains 50 μg of C. difficile toxin B in 50 mM Tris, 100 mM NaCl, pH 7.5 |
Shipping : | Room Temperature in continental US, may vary elsewhere. |
Gene Name | tcdB glycosylating toxin TcdB [ Clostridioides difficile ] |
Official Symbol | tcdB |
Synonyms | tcdB; glycosylating toxin TcdB; toxB; glycosylating toxin TcdB |
Gene ID | 31352216 |
UniProt ID | P18177 |
◆ Native Proteins | ||
TcdB-189C | Active Native Clostridium difficile Toxin B Protein | +Inquiry |
Not For Human Consumption!
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