Recombinant Bovine PRKAR1A
Cat.No. : | PRKAR1A-610B |
Product Overview : | Recombinant Bovine PRKAR1A is produced inE. coli.MW=43kDa. |
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Species : | Bovine |
Source : | E.coli |
Tag : | Non |
Description : | cAMP-dependent protein kinase type I-alpha regulatory subunit is an enzyme that in humans is encoded by the PRKAR1A gene. cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase A (PKA), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of PKA is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of PKA have been identified in humans. |
Purity : | ≥95% (SDS-PAGE). |
Formulation : | Liquid. In 10mM potassium phosphate, pH 6.8, containing 150mM NaCl, 14mM 2-mercaptoethanol, 1mM EDTA and 50% glycerol. |
Storage And Stability : | -80°C. Keep the glycerol stock solution of the enzyme permanently at -20°C while pipetting to avoid loss of inhibitory activity. Avoid freeze/thaw cycles. |
Gene Name | PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) [ Bos taurus ] |
Synonyms | PRKAR1A; protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1); cAMP-dependent protein kinase, regulatory subunit alpha 1; cAMP-dependent protein kinase type I-alpha regulatory subunit; EC 2.7.11.1 |
Gene ID | 615074 |
mRNA Refseq | NM_001076358 |
Protein Refseq | NP_001069826 |
UniProt ID | P00514 |
Chromosome Location | 19 |
Pathway | Apoptosis; Insulin signaling pathway |
Function | cAMP binding; cAMP-dependent protein kinase regulator activity; kinase activity; nucleotide binding; protein binding |
◆ Recombinant Proteins | ||
Prkar1a-5114M | Recombinant Full Length Mouse Prkar1a Protein, Myc/DDK-tagged | +Inquiry |
PRKAR1A-4333R | Recombinant Rat PRKAR1A Protein, His (Fc)-Avi-tagged | +Inquiry |
PRKAR1A-1770C | Recombinant Chicken PRKAR1A | +Inquiry |
PRKAR1A-333H | Recombinant Full Length Human PRKAR1A, His tagged | +Inquiry |
PRKAR1A-4870H | Recombinant Human PRKAR1A, His-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
PRKAR1A-1009HCL | Recombinant Human PRKAR1A cell lysate | +Inquiry |
Not For Human Consumption!
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